American depository receipts of European stocks were 0.2% lower at 121.88 on the Bank of New York Mellon Europe ADR Index on Wednesday morning.
Decliners in Continental Europe were led by CGG (CGG), a manufacturer of geophysical equipment, 4.8% lower, followed by Banco Bilbao Vizcaya Argentaria (BBVA), a Spanish financial group, down by 3.3% and Materialise (MTLS), a Belgian provider of 3D printing software and services, down by 2.0%. Technology investor Nokia (NOK) was 1.5% lower.
In the UK, gold producer Randgold Resources (GOLD) was 2.8% lower, followed by Avadel (AVDL), a specialty pharmaceutical company, down by 2.7%, and Akari Therapeutics (AKTX), a development-stage biopharmaceutical company, 2.6% lower. Royal Bank of Scotland (RBS) was 1.5% lower.
Gainers in Continental Europe were led by Nabriva Therapeutics (NBRV), an Austria-based clinical-stage biopharmaceutical company, up by 3.6%, followed by telecommunication company Telecom Italia (TI) and Luxottica (LUX), an Italian eyewear company, both 2.7% higher, and Logitech (LOGI), a Swiss hardware and software products developer, up by 1.5%.